Docentes


alexandre perfil

Alexandre de Almeida e Silva - alealsil@unir.br

Docente permanente

Linha de pesquisa: Biologia, biodiverdiversidade, ecologia e controle de vetores de interesse médico.

Currículo Lattes: http://lattes.cnpq.br/6440720566226268

Principais publicações:

1 - The Genome of Anopheles darlingi, the main neotropical malaria vector

2 - Amazonian biodiversity: a view of drug development for Leishmaniasis and malaria

3 - The Dynamics of Transmission and Spatial Distribution of Malaria in Riverside Areas of Porto Velho, Rondônia, in the Amazon Region of Brazil

4 - Larval food quantity affects development time, survival and adult biological traits that influence the vectorial capacity of Anopheles darlingi under laboratory conditions

5 - Antimicrobial peptides from Phyllomedusa frogs: from biomolecular diversity to potential nanotechnologic medical applications


Andreimar perfil

Andreimar Martins Soaresandreimar@fiocruz.br

Docente permanente

Linha de pesquisa: Bioprospecção e caracterização de moléculas da biodiversidade amazônica úteis à saúde humana. Nanotecnologia aplicada às doenças tropicais.

Currículo Lattes: http://lattes.cnpq.br/1721501040953897

Principais publicações:

1 - Structural and functional characterization of BnSP-7, a Lys49 myotoxic phospholipase A2 homologue from Bothrops neuwiedi pauloensis venom

2 - Myotoxic phospholipases A2 in Bothrops snake venoms: Effects of chemical modifications on the enzymatic and pharmacological properties of bothropstoxins from Bothrops jararacuçu

3 - Structural and functional characterization of neuwiedase, a non-hemorrhagic fibrin(ogen)olytic metalloprotease from Bothrops neuwiedi snake venom

4 - Chemical Modifications of Phospholipases A2 from Snake Venoms: Effects on Catalytic and Pharmacological Properties

5 - Medicinal plants with inhibitory properties against snake venoms


Carla perfil

Carla Freire Celedônio Fernandescarlaceledonio@fiocruz.br

Docente permanente

Linha de pesquisa: Nanotecnologia aplicada às doenças tropicais.

Currículo Lattes: http://lattes.cnpq.br/3922481112087617

Principais publicações:

1 - Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10a6)

2 - Antitumoral Activity of Snake Venom Proteins: New Trends in Cancer Therapy

3 - Cloning and molecular characterization of the orphan carrier protein Slc10a4: Expression in cholinergic neurons of the rat central nervous system

4 - Molecular and phylogenetic characterization of a novel putative membrane transporter (SLC10A7), conserved in vertebrates and bacteria

5 - The novel putative bile acid transporter SLC10A5 is highly expressed in liver and kidney


Carolina perfil

Carolina Bioni Garcia Telescarolinateles@fiocruz.br

Docente permanente

Linha de pesquisa: Bioprospecção e caracterização de moléculas da biodiversidade amazônica úteis à saúde humana. Nanotecnologia aplicada às doenças tropicais.

Currículo Lattes: http://lattes.cnpq.br/8279471785523666

Principais publicações:

1 - Activity of the Lupane isolated from Combretum leprosum against Leishmania amazonensis promastigotes

2 - Epidemiological aspects of American cutaneous leishmaniasis and phlebotomine sandfly population, in the municipality of Monte Negro, State of Rondônia, Brazil.

3 - Description of a new phlebotomine species (Diptera: Psychodidae, Phlebotominae) and new records of sand flies from the State of Acre, northern Brazil

4 - A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitro

5 - Ecological aspects and molecular detection of Leishmania DNA Ross (Kinetoplastida: Trypanosomatidae) in phlebotomine sandflies (Diptera: Psychodidae) in terra firme and várzea environments in the Middle Solimões Region, Amazonas State, Brazil


Christian

Christian Collins Kuehnchristian.collins@unir.br

Docente colaborador

Linha de pesquisa: Fisiopatologia e Epidemiologia de Doenças Tropicais

Currículo Lattes: http://lattes.cnpq.br/6590442392256649

Principais publicações:

1 - Enhanced protection by melatonin and meloxicam combination in experimental infection by Trypanosoma cruzi

2 - Evaluation of the schistosomicidal activity of the steroidal alkaloids from Solanum lycocarpum fruits

3 - Melatonin and dehydroepiandrosterone combination: does this treatment exert a synergistic effect during experimental Trypanosoma cruzi infection?

4 - In vitro Leishmanicidal and Cytotoxic Activities of the Glycoalkaloids from Solanum lycocarpum (Solanaceae) Fruits

5 - Protective actions of melatonin against heart damage during chronic Chagas disease 


deusilene perfil

Deusilene Sousa Vieiradeusilene@fiocruz.br

Docente permanente

Linha de pesquisa: Fisiopatologia e Epidemiologia de Doenças Tropicais.

Currículo Lattes: http://lattes.cnpq.br/9563593830946503

Principais publicações:

1 - Molecular epidemiology of dengue type 3 virus in Brazil and Paraguay, 2002-2004

2 - Characterization of Hepatitis B virus (HBV) genotypes in patients from Rondônia, Brazil

3 - Notification of the first isolation of Cacipacore virus in a human in the State of Rondônia, Brazil

4 - Distribution of hepatitis c virus (hcv) genotypes in patients with chronic infection from Rondônia, Brazil

5 - Development of cost-effective real-time PCR test: to detect a wide range of HBV DNA concentrations in the western amazon region of Brazil


dhelio perfil

Dhélio Batista Pereira - dhelio@unir.br

Docente permanente

Linha de Pesquisa: Fisiopatologia e Epidemiologia de Doenças Tropicais

Currículo Lattes: http://lattes.cnpq.br/7206230938221234

Principais publicações:

1 - Malaria primes the innate immune response due to interferon-  induced enhancement of toll-like receptor expression and function

2 - Malaria-Induced NLRP12/NLRP3-Dependent Caspase-1 Activation Mediates Inflammation and Hypersensitivity to Bacterial Superinfection

3 - Neutrophil Paralysis in Plasmodium vivax Malaria

4 - The CD14+CD16+ Inflammatory Monocyte Subset Displays Increased Mitochondrial Activity and Effector Function During Acute Plasmodium vivax Malaria

5 - Induction of Inhibitory Receptors on T Cells During Plasmodium vivax Malaria Impairs Cytokine Production 


fernando perfil

Fernando Berton Zanchi fbzanchi@hotmail.com

Docente permanente 

Linha de pesquisa: Genética e bioinformática aplicada às doenças infecciosas e parasitárias.

Currículo Lattes: http://lattes.cnpq.br/0564343474986429

Principais publicações:

1 - Inhibition of the Myotoxicity Induced by Bothrops jararacussu Venom and Isolated Phospholipases A2 by Specific Camelid Single-Domain Antibody Fragments

2 - Snake Venom L-Amino Acid Oxidases: Trends in Pharmacology and Biochemistry

3 - Cross-reactive anti-PfCLAG9 antibodies in the sera of asymptomatic parasite carriers of Plasmodium vivax

4 - Design and Heterologous Expression of Dengue Virus Envelope Protein (E) Peptides and Their Use for Serological Diagnosis

5 - Biological characterization of the Amazon coral Micrurus spixii snake venom: Isolation of a new neurotoxic phospholipase A2


gabriel perfil

Gabriel Eduardo Melim Ferreira gabriel.ferreira@fiocruz.br

Docente permanente

Linha de pesquisa: Genética e bioinformática aplicada às doenças infecciosas e parasitárias.

Currículo Lattes: http://lattes.cnpq.br/5234521391957594

Principais publicações:

1 - Comparative Microsatellite Typing of New World Leishmania infantum Reveals Low Heterogeneity among Populations and Its Recent Old World Origin

2 - Molecular and Behavioral Differentiation among Brazilian Populations of Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae)

3 - The Genetic Structure of Leishmania infantum Populations in Brazil and Its Possible Association with the Transmission Cycle of Visceral Leishmaniasis

4 - Multilocus analysis of introgression between two sand fly vectors of leishmaniasis

5 - Peridomiciliary colonies of Triatoma vitticeps (Stal, 1859) (Hemiptera, Reduviidae, Triatominae) infected with Trypanosoma cruzi in rural areas of the state of Espírito Santo, Brazil


Genimar

Genimar Rebouças Julião grjuliao@fiocruz.br

Docente permanente

Linha de pesquisa: Biologia, biodiverdiversidade, ecologia e controle de vetores de interesse médico.

Currículo Lattes: http://lattes.cnpq.br/9010904883568247

Principais publicações:

1 - Anthropic effects on sand fly (Diptera: Psychodidae) abundance and diversity in an Amazonian rural settlement, Brazil

2 - Unexpected high diversity of galling insects in the Amazonian upper canopy: the savanna out there

3 - Hiding from defenders: localized chemical modification on the leaves of an Amazonian ant-plant induced by a gall-making insect (Diptera:Cecidomyiidae)"

4 - Calodium hepaticum: Household Clustering Transmission and the Finding of a Source of Human Spurious Infection in a Community of the Amazon Region

5 - Measuring Mosquito Diversity Patterns in an Amazonian Terra Firme Rain Forest


 Jansen

Jansen Fernandes de Medeiros jmedeiro@fiocruz.br

Docente permanente

Linha de pesquisa: Biologia, biodiverdiversidade, ecologia e controle de vetores de interesse médico.

Currículo Lattes: http://lattes.cnpq.br/5425946423248431

Principais publicações:

1 - Calliphoridae (Diptera) coletados em cadáveres humanos no Rio Grande do Norte

2 - Current profile of Mansonella ozzardi (Nematoda: Onchocercidae) in communities along the Ituxi river, Lábrea municipality, Amazonas, Brazil

3 - Mansonella ozzardi in Brazil: prevalence of infection in riverine communities in the Purus region, in the state of Amazonas

4 - Mansonella ozzardi in Amazonas, Brazil: prevalence and distribution in the municipality of Coari, in the middle Solimões River

5 - A deep insight into the sialotranscriptome of the mosquito, Psorophora albipes


juliana perfil

Juliana Pavan Zuliani juliana.zuliani@unir.br

Docente permanente

Linha de pesquisa: Bioprospecção e caracterização de moléculas da biodiversidade amazônica úteis à saúde humana.

Currículo Lattes: http://lattes.cnpq.br/9093880214338747

Principais publicações:

1 - Neutrophils do not contribute to local tissue damage, but play a key role in skeletal muscle regeneration, in mice injected with Bothrops asper snake venom

2 - Inflammatory events induced by Lys-49 and Asp-49 phospholipases A isolated from snake venom: role of catalytic activity

3 - Inflammatory effects of BaP1 a metalloproteinase isolated from Bothrops asper snake venom: Leukocyte recruitment and release of cytokines

4 - Activation of cellular functions in macrophages by venom secretory Asp-49 and Lys-49 phospholipases A

5 - Inflammatory effects of snake venom metalloproteinases


 leonardo perfil

Leonardo de Azevedo Calderoncalderon@unir.br

Docente permanente

Linha de pesquisa: Bioprospecção e caracterização de moléculas da biodiversidade amazônica úteis à saúde humana; Nanotecnologia aplicada às doenças tropicais.

Currículo Lattes: http://lattes.cnpq.br/6910026933721706

Principais publicações:

1 - Antitumoral Activity of Snake Venom Proteins: New Trends in Cancer Therapy

2 - Amazonian biodiversity: a view of drug development for Leishmaniasis and malaria

3 - Antimicrobial peptides from Phyllomedusa frogs: from biomolecular diversity to potential nanotechnologic medical applications

4 - Purification and pH stability characterization of a chymotrypsin inhibitor from Schizolobium parahyba seeds

5 - Serine protease inhibitors from Amazon leguminosae seeds: purification and preliminary characterization of two chymotrypsin inhibitors from Inga umbratica


 najla perfil 

Najla Benevides Matosnajlamatos@fiocruz.br

Docente permanente

Linha de Pesquisa: Fisiopatologia e Epidemiologia de Doenças Tropicais

Currículo Lattes: http://lattes.cnpq.br/4963470094090382

Principais publicações:

1 - Etiology of diarrheal infections in children of Porto Velho (Rondonia, Western Amazon region, Brazil)

2 - HasB, the Serratia marcescens TonB Paralog, Is Specific to HasR

3 - The Hem and Has haem uptake systems in Serratia marcescens

4 - The prevalence of norovirus, astrovirus and adenovirus infections among hospitalised children with acute gastroenteritis in Porto Velho, state of Rondônia, western Brazilian Amazon

5 - Isolation, structural and functional characterization of a new Lys49 phospholipase A2 homologue from Bothrops neuwiedi urutu with bactericidal potential


 quintino perfil

Quintino Moura Dias Júnior - quintinojunior@fiocruz.br

Docente permanente

Linha de pesquisa: Bioprospecção e caracterização de moléculas da biodiversidade amazônica úteis à saúde humana

Currículo Lattes: http://lattes.cnpq.br/3352640545833230

Principais publicações:

1 - Morphine peripheral analgesia depends on activation of the PI3K /AKT/nNOS/NO/KATP signaling pathway

2 - Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats

3 - Antinociceptive Effect of Stimulating the Occipital or Retrosplenial Cortex in Rats

4 - The effect of intrathecal gabapentin on neuropathic pain is independent of the integrity of the dorsolateral funiculus in rats

5 - Muscarinic and ?1-adrenergic mechanisms contribute to the spinal mediation of stimulation-induced antinociception from the pedunculopontine tegmental nucleus in the rat


ricardo perfil

Ricardo de Godoi Matos Ferreira rcgmf@gmail.com

Docente permanente

Linha de pesquisa: Genética e bioinformática aplicada às doenças infecciosas e parasitárias.

Currículos Lattes: http://lattes.cnpq.br/0175278011664600

Principais publicações:

1 - Association of Genetic Variants in Alcohol Dehydrogenase 4 With Alcohol Dependence in Brazilian Patients

2 - Major gene and multifactorial inheritance of mandibular prognathism

3 - Extense variant gene family repertoire overlap in Western Amazon Plasmodium falciparum isolates?

4 - The association of genetic markers and malaria infection in the Brazilian Western Amazonian region

5 - Association of MAO A polymorphism and alcoholism in Brazilian females

 

 

Soraya dos Santos Pereira  soraya.santos@fiocruz.br 

Docente permanente 

Linha de pesquisa: Bioprospecção e caracterização de moléculas da biodiversidade amazônica úteis à saúde humana. 

Currículos Lattes: http://lattes.cnpq.br/5067608075094162 

Principais publicações: 

1 - Camelid Single-Domain Antibodies (VHHs) against Crotoxin: A Basis for Developing Modular Building Blocks for the Enhancement of Treatment or Diagnosis of Crotalic Envenoming

2 - Effect of BjcuL, a lectin isolated from Bothrops jararacussu, on human peripheral blood mononuclear cells 

3 - Molecular quantitative assay for esterase-mediated organophosphate resistance in Rhipicephalus microplus

4 - Camelid Single-Domain Antibodies As an Alternative to Overcome Challenges Related to the Prevention, Detection, and Control of Neglected Tropical Diseases

5 - Inhibition of the Myotoxicity Induced by Bothrops jararacussuVenom and Isolated Phospholipases A2 by Specific Camelid Single-Domain Antibody Fragments